Two sample MR report
ELP5_Monocyte (Mono) against finn-b-ASTHMA_ALLERG_EXMORE
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | 0.0544438 | 0.1486027 | 0.7225525 |
| Weighted median | 11 | -0.0829997 | 0.0198685 | 0.0000295 |
| Inverse variance weighted | 11 | -0.1046554 | 0.0145101 | 0.0000000 |
| Simple mode | 11 | -0.0817573 | 0.0317221 | 0.0275438 |
| Weighted mode | 11 | -0.0812590 | 0.0276766 | 0.0148866 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.304907 | 9 | 0.8902232 |
| Inverse variance weighted | 5.462200 | 10 | 0.8582453 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.1079217 | 0.10032 | 0.3100194 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002298 | 1e-07 | TRUE | 0.1548644 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
